Angioid streaks of the fundus
http://purl.obolibrary.org/obo/HP_0001102
Irregular lines in the deep retina that are typically configured in a radiating fashion and emanate from the optic disc. Angioid streaks are crack-like dehiscences in abnormally thickened and calcified Bruch's membrane, resulting in atrophy of the overlying retinal pigment epithelium. They may be associated with a number of endocrine, metabolic, and connective tissue abnormalities but are frequently idiopathic. [ PMID:30844178 ORCID:0000-0003-0986-4123 HPO:probinson ]
Term info
- UMLS:C0002982
- MSH:D000793
Angioid streaks result from breaks in a weakened Bruch's membrane.
Irregular lines in the deep retina that are typically configured in a radiating fashion and emanate from the optic disc. Angioid streaks are crack-like dehiscences in abnormally thickened and calcified Bruch's membrane, resulting in atrophy of the overlying retinal pigment epithelium. They may be associated with a number of endocrine, metabolic, and connective tissue abnormalities but are frequently idiopathic.
Angioid streaks, Knapp streaks, Angioid streaks, retina, Laquer cracks of the retina, Angioid streaks of the retina
HP:0001102