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Increased iduronate sulfatase level

^ http://purl.obolibrary.org/obo/HP_0003538

An increased level of iduronate-2-sulfatase activity in the blood. [ HPO:probinson ]

Term info

database cross reference
  • UMLS:C4025599
  • UMLS:C2673363
comment

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene are associated with Mucopolysaccharidosis Type II. Increased serum iduronate-2-sulfatase is observed in mucolipidosis II alpha/beta.

definition

An increased level of iduronate-2-sulfatase activity in the blood.

has exact synonym

Increased serum iduronate sulfatase level

has related synonym

Increased serum iduronate sulfatase

id

HP:0003538

Term relations