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Foam cells

^ http://purl.obolibrary.org/obo/HP_0003651

The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance. [ HPO:probinson ]

Term info

database cross reference
  • UMLS:C0016390
  • MSH:D005487
  • SNOMEDCT_US:16980002
comment

Foam cells may contain polymorphic cytoplasmic inclusions consisting of lamellar osmiophilic membranes on electron microscopy.

definition

The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance.

has alternative id

HP:0003650

has exact synonym

Foamy histiocytes, Lipid-laden histiocytes, Presence of foam cells, Foamy macrophages

id

HP:0003651

Term relations

Subclass of: