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Reduced protein S activity

^ http://purl.obolibrary.org/obo/HP_0004855

An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C. [ HPO:probinson ]

Term info

database cross reference
  • SNOMEDCT_US:1563006
  • MSH:D018455
  • UMLS:C4025284
  • UMLS:C0242666
comment

Protein S functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa in the coagulation pathway. Therefore, a defect in protein S is associated with an increased risk of thrombosis.

definition

An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C.

has narrow synonym

Protein S deficiency

id

HP:0004855