Abnormality of the intrinsic pathway

http://purl.obolibrary.org/obo/HP_0010989

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade. [ HPO:probinson ]

Tree view
Term history

Term info

database cross reference

UMLS:C4023610

comment

The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

created by

peter

creation date

2011-02-08T04:26:55Z

definition

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade.

HP:0010989

Term relations

Subclass of:

Abnormality of the coagulation cascade