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Acantholysis

^ http://purl.obolibrary.org/obo/HP_0100792

The loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes. [ HPO:sdoelken ]

Term info

database cross reference
  • UMLS:C0241128
  • UMLS:C0000887
  • SNOMEDCT_US:441837004
  • MSH:D000051
  • SNOMEDCT_US:43327007
comment

Acantolysis results in a positive Nikolsky's sign in which slight rubbing of the skin results in exfoliation of the outermost layer.

created by

doelkens

creation date

2011-06-08T03:22:24Z

definition

The loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes.

has related synonym

Nikolsky's sign

id

HP:0100792

Term relations