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autoimmune encephalopathy with parasomnia and obstructive sleep apnea

^ http://purl.obolibrary.org/obo/MONDO_0018489

Autoimmune encephalopathy with parasomnia and obstructive sleep apnea is a rare neurologic disorder characterized by a unique non-REM and REM parasomnia with sleep breathing dysfunction, gait instability and repetitive episodes of respiratory insufficiency, as well as autoantibodies against IgLON5. Patients may present stridor, chorea, limb ataxia, abnormal ocular movements, and bulbar symptoms (i.e. dysphagia, dysarthria, episodic central hypoventilation) with normal brain MRI. Excessive day sleepiness and cognitive deterioration have also been reported. [ Orphanet:420789 ]

Term info

database cross reference
  • SCTID:765751002 (MONDO:equivalentTo)
  • Orphanet:420789 (MONDO:equivalentTo)
  • UMLS:CN237490 (MONDO:equivalentTo)
Subsets

ordo_disease

definition

Autoimmune encephalopathy with parasomnia and obstructive sleep apnea is a rare neurologic disorder characterized by a unique non-REM and REM parasomnia with sleep breathing dysfunction, gait instability and repetitive episodes of respiratory insufficiency, as well as autoantibodies against IgLON5. Patients may present stridor, chorea, limb ataxia, abnormal ocular movements, and bulbar symptoms (i.e. dysphagia, dysarthria, episodic central hypoventilation) with normal brain MRI. Excessive day sleepiness and cognitive deterioration have also been reported.

exactMatch

http://identifiers.org/snomedct/765751002, http://linkedlifedata.com/resource/umls/id/CN237490, http://purl.obolibrary.org/obo/Orphanet_420789

has exact synonym

anti-IgLON5 syndrome, anti-IgLON5 disease

id

MONDO:0018489