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myelodysplastic syndrome

^ http://purl.obolibrary.org/obo/MONDO_0018881

A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) [ NCIT:C3247 ]

Term info

database cross reference
  • SCTID:109995007 (MONDO:equivalentTo)
  • ICDO:9989/3 (NCIT:C3247)
  • DOID:0050908 (MONDO:equivalentTo)
  • Orphanet:52688 (OMIM:614286)
  • ONCOTREE:MDS (MONDO:equivalentTo)
  • GARD:0007132 (MONDO:equivalentTo)
  • EFO:0000198 (MONDO:equivalentTo)
  • UMLS:C3463824 (Orphanet:52688)
  • OMIM:614286 (Orphanet:52688/e)
  • ICD9:238.7 (DOID:0050908)
  • UMLS:C0033027 (MONDO:equivalentTo)
  • NCIT:C3247 (MONDO:equivalentTo)
  • MedDRA:10028532 (Orphanet:52688/e)
  • ICD9:238.75 (MONDO:i2s)
Subsets

disease_grouping, ordo_group_of_disorders

abbreviation
MDS [ MONDO:Lexical OMIM:614286 NCIT:C3247 ]

abbreviation
MDS-U [ doi:10.5772/intechopen.82532 ]

abbreviation
MDS, unclassifiable [ doi:10.5772/intechopen.82532 ]

IAO 0000233

https://github.com/monarch-initiative/mondo/issues/5268, https://github.com/monarch-initiative/mondo/issues/4521

closeMatch

http://identifiers.org/meddra/10028532

definition

A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)

exactMatch

http://purl.obolibrary.org/obo/Orphanet_52688, https://omim.org/entry/614286, http://linkedlifedata.com/resource/umls/id/C3463824, http://purl.obolibrary.org/obo/NCIT_C3247, http://linkedlifedata.com/resource/umls/id/C0033027, http://purl.obolibrary.org/obo/DOID_0050908, http://identifiers.org/snomedct/109995007

has exact synonym

oligoblastic leukemia, MDS, unclassifiable, preleukemia, myelodysplastic syndrome, somatic, myelodysplastic neoplasm, dysmyelopoietic syndrome, myelodysplasia, hematopoeitic - myelodysplastic syndrome (MDS), smoldering leukemia, myelodysplastic syndrome, unclassifiable, myelodysplastic syndromes, MDS-U, myelodysplastic syndrome/neoplasm, myelodysplastic syndrome, MDS

has related synonym

myelodysplastic syndrome, susceptibility to

id

MONDO:0018881